Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-11-14
1998-10-06
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544 584, 544127, 546113, A61K 3144, C07D47104
Patent
active
058176713
ABSTRACT:
This invention provides 5-HT.sub.1F agonists of Formula I: ##STR1## where A--B, X, and R are as defined in the specification. The invention also encompasses pharmaceutical formulations employing compounds of Formula I as well as methods of treating conditions associated with 5-HT.sub.1F activation employing these compounds or compositions. The invention also provides intermediates useful for the preparation of the compounds of Formula I.
REFERENCES:
patent: 5051412 (1991-09-01), Macor
patent: 5169947 (1992-12-01), Macor
patent: 5521196 (1996-05-01), Audia et al.
patent: 5521197 (1996-05-01), Audia
patent: 5604240 (1997-02-01), Chambers et al.
patent: 5708008 (1998-01-01), Audia et al.
Filla Sandra Ann
Johnson Kirk W.
Phebus Lee A.
Schaus John Mehnert
Boone David E.
Eli Lilly and Company
Ramsuer Robert W.
Titus Robert D.
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