5-HT.sub.1A ligands

Details 5-HT.sub.1A ligands 5-HT.sub.1A ligands

1997-08-18

2000-05-02

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 141, 424 145, 544360, A61K 2104, C07D40100

Patent

active

060569425

ABSTRACT:
Selective 5-HT.sub.1A antagonists radiolabelled with .sup.3 H or .sup.11 C are radiolabelled ligands useful, for example, in pharmacological screening procedures and in positron emission tomography (PET) studies.

REFERENCES:
patent: 4994258 (1991-02-01), Burn et al.
Lever, et al., "Synthesis and In Vivo Characterization of O-(t)-(N-1-[-11]Methyl)-2-Br-LSD," Nucl. Med. Biol., vol.16, No. 7, pp. 697-704, 1989.
Chem. Abst. 106(9): 63908e, (1986).
Chem. Abst. 104(11): 8248r, (1986).
H. Sijbesma, Euro. J. Pharm., vol. 187, No. 2 (1990) 209-223.
Chem. Abst. 114(3): 17928d, (1990).
Chem. Abst. 114(25): 240437p, (1991).
Chem. Abst. 117(11): 103411y, (1992).
D. Julius, Annu. Rev. Neurosci., 1991, 14:335-360.
C. Crouzel et al., Nucl. Med. Biol., vol. 19, No. 8, 857-870 (1992).

Affiliated with

Also associated with

Rating

5-HT.sub.1A ligands does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-HT.sub.1A ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-HT.sub.1A ligands will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1591856