5-HT 7 receptor antagonists

Details 5-HT 7 receptor antagonists 5-HT 7 receptor antagonists

2009-05-22

2010-02-16

Parsa, Jafar (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S914000, C514S923000, C546S099000

Reexamination Certificate

active

07662862

ABSTRACT:
The invention relates to compounds having pharmacological activity towards the 5-HT7 receptor, and more particularly to some 2,2a,4,5-tetrahydro-1H-3-aza-acenaphthylen substituted sulfonamide compounds, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which 5-HT is involved, such as CNS disorders.

REFERENCES:
patent: 0 021 580 (1983-12-01), None
patent: 0 076 072 (1987-05-01), None
patent: 0 937 715 (1999-08-01), None
patent: WO 97/29097 (1997-08-01), None
patent: WO 97/48681 (1997-12-01), None
patent: WO 97/49695 (1997-12-01), None
patent: WO 99/24022 (1999-05-01), None
patent: WO 00/00472 (2000-01-01), None
patent: WO 03/048118 (2003-06-01), None
De Ponti et al., Drugs, vol. 61, pp. 317-332, 2001.
Grunewald et al., J. Med. Chem., vol. 31(2), pp. 433-444, 1988.
Hodge Markgraf et al., Heterocycles, vol. 29(12), pp. 2399-2402, 1989.
Huffman et al., J. Org. Chem., vol. 36(1), pp. 111-117, 1971.
Lovenberg et al., Neuron, vol. 11, pp. 449-458, 1993.
Munson et al., Anal. Biochem., vol. 107, pp. 220-239, 1980.
Pelletier et al., J. Org. Chem., vol. 52, pp. 616-622, 1987.
Read et al., Br. J. Pharmacol., vol. 140, pp. 53-60, Jul. 29, 2003.
Schoeffer et al., Br. J. Pharmacol., vol. 117, pp. 993-994, 1996.
Terron, J.A., Br. J. Pharmacol., vol. 121, pp. 563-571, 1997.
Terron, J.A., IDrugs, vol. 1(3), pp. 302-301, 1998.
Terron, J.A., Eur. J. Pharmacol., vol. 439, pp. 1-11, 2002.
Vermeulen et al., J. Med Chem., vol. 47, pp. 5451-5466, Sep. 23, 2004.
Wesolowska, A., Polish J. Pharmacol., vol. 54, pp. 327-341, 2002.
European Patent Office, European Search Report for EP 04380280.0, issued May 12, 2005.
PCT International Search Report, PCT/EP2005/014044, dated Feb. 27, 2006.

Affiliated with

Also associated with

Rating

5-HT 7 receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-HT 7 receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-HT 7 receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4231204