5-fluorooxindole-3-carboxylic acid ester

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S486000, C548S484000, C514S412000, C514S415000

Reexamination Certificate

active

07342040

ABSTRACT:
A 5-fluorooxindole-3-carboxylic acid ester represented by a formula (2):wherein R1is a group selected from the group consisting of an unsubstituted or substituted alkyl group having 1 to 10 carbon atoms, an unsubstituted or substituted cycloalkyl group having 3 to 7 carbon atoms, an aralkyl group having 7 to 10 carbon atoms or an aryl group having 6 to 14 carbon atoms.

REFERENCES:
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Kadin et al (1989): STN International HCAPLUS database, Columbus (OH), accession No. 1989: 23728.
E.A. Kraynack et al., “An Improved Procedure for the Regiospecific Synthesis of Electron Deficient 4- and 6-Substituted Isatins”,Tetrahedron Letters, 39(42), pp. 7679-7682 (1998).
G.J. Quallich et al., “A General Oxindole Synthesis”,SYNTHESIS, pp. 51-53, (Jan. 1993).
Kazumi Okuro et al., “Copper-Catalyzed Reaction of Aryl Iodides with Active Methylene Compounds,”J. Org. Chem., (1993), 58(26), pp. 7606-7607.

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