5-fluoro-PGI.sub.2 compounds

Details 5-fluoro-PGI.sub.2 compounds 5-fluoro-PGI.sub.2 compounds

1985-03-08

1987-06-02

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540544, 540596, 544153, 544335, 544376, 546196, 548525, C07D307935

Patent

active

046705694

ABSTRACT:
The present invention relates to 5-fluoro-PGI.sub.2 derivatives of Formula I. These compounds are useful for the treatment of platelet dysfunction. Also disclosed is the process for preparing them and the appropriate intermediates.

REFERENCES:
patent: 4324730 (1982-04-01), Fried
Bindra et al., Prostaglandin Synthesis, Academic Press, pp. 71-75 (1977).
Nakai et al., Chem. Letters, pp. 1499-1502 (1979).
Bannai et al., Yuki Gosei Kagaku Kyokashi, 42(9), pp. 794-808 (1984).

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