5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives

Details 5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives 5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives

1979-06-06

1984-09-18

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 23, A61K 3170, C07H 1906, C07H 1908

Patent

active

044723865

ABSTRACT:
5-Fluoro-(.beta.-uridine or 2'-deoxy-.beta.-uridine) derivatives having an acyl group at the 3-position of the molecule. These compounds are useful as carcinostatic agent. This disclosure relates to such compounds, a process for producing the same and a carcinostatic agent comprising such a compound.

REFERENCES:
patent: 3309359 (1967-03-01), Dreschensky et al.
patent: 3975367 (1976-08-01), Gish et al.
Heidelberger, C. et al., Biochim. Biophys. Acta., vol. 76, 312-314, 1963.
Khwaja, T. et al., J. Of Medicinal Chemistry, vol. 13, 64-69, 1970.
Heidelberger, C. et al., Proc. Soc. Exper. Biol. & Med., vol. 97, 470-475, 1958.

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