5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602433, 424250, 544370, C07D24304, A61K 31495

Patent

active

044605080

ABSTRACT:
5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines, for example compounds of the formula ##STR1## in which e.g., R.sub.1, R.sub.2 and R.sub.4 are hydrogen, R.sub.3 is methyl and C.sub.n H.sub.2n is CH.sub.2 CH.sub.2, have neurcleptic and/or antihistaminic activity. The synthesis, pharmaceutical compositions and methods of treatment utilizing such compounds are described.

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William B. Wright, Jr. et al. Derivatives of 11 (1-Piperazinyl-5H-pyrrolo[2,1-c][1,4]Benzodiazepine as Central Nervous System Agents, J. Med. Chem. 1980, 23,462-465.

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