5-Diazacycloalkyl imidazo[1,2-c][1,3]benzodiazepines

Details 5-Diazacycloalkyl imidazo[1,2-c][1,3]benzodiazepines 5-Diazacycloalkyl imidazo[1,2-c][1,3]benzodiazepines

1982-11-29

1984-07-17

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260239BC, 2602433, 2602456, 2604537, 260464, 424273R, 544229, 544370, 548335, 548342, 548343, 564254, A61K 31415, C07D48704

Patent

active

044605870

ABSTRACT:
5-Diazacycloalkylimidazo[1,2-c][1,3]benzodiazepines, for example compounds of the formula ##STR1## in which e.g., R.sub.1, R.sub.2 and R.sub.4 are hydrogen, R.sub.3 is methyl and C.sub.n H.sub.2n is CH.sub.2 CH.sub.2, have neuroleptic and/or antihistaminic activity. The synthesis, pharmaceutical compositions and methods of treatment utilizing such compounds are described.

REFERENCES:
patent: 3539573 (1970-11-01), Schmutz et al.
patent: 3933794 (1976-01-01), Hester, Jr. et al.
patent: 4192803 (1980-03-01), Wright et al.
patent: 4280957 (1981-07-01), Walser et al.
patent: 4337198 (1982-06-01), Sorg et al.
patent: 4391808 (1983-07-01), Vlattas
William B. Wright, Jr. et al., Derivatives of 11[1-piperazinyl]-5H-Pyrrolo[2,1-c][1,4]Benzodiazepine as Central Nervous System Agents, J. Med. Chem., 1980, 23, 462-465.

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