5'-deoxy-5',5'-dihalo adenosines and purine analogues

Details 5'-deoxy-5',5'-dihalo adenosines and purine analogues 5'-deoxy-5',5'-dihalo adenosines and purine analogues

1989-07-14

1991-03-05

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, C07H 19167, C07H 19173, C07H 1919

Patent

active

049979256

ABSTRACT:
This invention relates to certain 5',5'-dihaloaristeromycin/adenosine derivatives which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.

REFERENCES:
Bennett et al., Mol. Pharmacol, 29, 383 (1986).
De Clercq, Biochem. Pharmacol, 36, 2567-75 (1987).

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