5'-deoxy-4',5'-unsaturated-5'-substituted adenosines

Details 5'-deoxy-4',5'-unsaturated-5'-substituted adenosines 5'-deoxy-4',5'-unsaturated-5'-substituted adenosines

1989-11-29

1991-03-05

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, C07H 19167, C07H 19173

Patent

active

049979248

ABSTRACT:
This invention relates to certain aristeromycin/adenosine derivatives which are useful in inhibiting AdoMet-dependent transmethylation and in the treatment of patients afflicted with neoplastic or viral disease states.

REFERENCES:
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Sandstrom et al. Drugs, v. 34, 372-390 (1987).
Mitsuya et al., "Protection of T Cells Against Infectivity and Cytopathic Effect of HTLV-III in Vitro" in "Retroviruses in Human Lymphoma/Leukemia", M. Miwa et al., eds., 1985, pp. 277-288.

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