5-deaza-10-oxo-and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids

Details 5-deaza-10-oxo-and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids 5-deaza-10-oxo-and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids

1994-02-14

1996-09-03

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D48704, C07D47104

Patent

active

055525458

ABSTRACT:
5-Deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid derivatives are provided as agents useful for treating susceptible neoplasms in mammals. Pharmaceutical formulations and intermediates are also provided.

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