5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid

Details 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid

1992-07-07

1994-06-14

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 41, C07C 2900

Patent

active

053211502

ABSTRACT:
5-Deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid derivatives are provided as agents useful for treating susceptible neoplasms in mammals. Pharmaceutical formulations and intermediates are also provided.

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