5-cyanopyridine-2-diazohydroxide, basic salts and use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546289, A61K 3144

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active

048164682

ABSTRACT:
The title compounds are provided as well as a method for their production, pharmaceutical compositions comprising the compounds, and methods of treatment using the compounds in dosage form. The compounds of the invention have pharmacological properties and are useful cytostatic agents and cell growth inhibiting agents. ##STR1##

REFERENCES:
patent: 4636564 (1987-01-01), Baker et al.
Goldin, A. et al., "Progress Report on Screening Program", Cancer Treatment Reviews (1980) pp. 167-176.
Bunton, C. A. et al, "Decomposition of Pyridine-2- and -4-diazotates", J.A.C.S., 1974, 96, pp. 3267-3275.

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