5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine

Details 5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine 5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine

1984-02-27

1985-09-10

Hollrah, Glennon H.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D 4108

Patent

active

045405140

ABSTRACT:
The invention relates to a process for the manufacture of the known 5-carbamoyl-10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine of the formula III which is characterized in that, for example, 5-cyano-5H-dibenz[b,f]azepine of the formula I is nitrated to form 5-cyano-10-nitro-5H-dibenz[b,f]azepine of the formula II, this is subjected to hydrolysis, then reduction, then the reduction product contained in the reaction mixture is subjected to hydrolysis and the end product of the formula III is isolated in pure form.
The process is illustrated by the following reaction scheme: ##STR1## The invention relates also to new intermediates produced in these reactions.

REFERENCES:
patent: 3637661 (1972-01-01), Schindler
patent: 3642775 (1972-02-01), Schindler
patent: 3716640 (1973-02-01), Schindler
patent: 3792042 (1974-02-01), Fouche
patent: 4235895 (1980-11-01), Blattner et al.

Affiliated with

Also associated with

Rating

5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-Cyano- and 5-carbamoyl-10-nitro-5H-dibenz[b,f]azepine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1427625