5-chloro-s-triazolo[4,3-a]-pyridine-7-carboxylic acids, useful a

Details 5-chloro-s-triazolo[4,3-a]-pyridine-7-carboxylic acids, useful a 5-chloro-s-triazolo[4,3-a]-pyridine-7-carboxylic acids, useful a

1985-08-01

1987-03-17

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D47104

Patent

active

046508724

ABSTRACT:
5-Chloro-3-(substituted)-s-triazolo[4,3-a]pyridine-7-carboxylic acids useful as antiallergic agents are described herein. The compounds are prepared from an appropriate acyl 6-chloro-2-hydrazinopyridine, substituted at the 4-position with a trichloromethyl group or a cyano group, by reaction with polyphosphoric acid.

REFERENCES:
patent: 3597423 (1971-08-01), Wiedemann et al.
W. W. Paudler & R. Brumbaugh, Chem. Ind., 24, 991 (1966).
K. T. Potts & H. R. Burton, J. Org. Chem., 31, 251 (1966).

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