5-benzyl barbiturate derivatives

Details 5-benzyl barbiturate derivatives 5-benzyl barbiturate derivatives

1990-04-12

1992-08-25

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514271, 544299, 544301, 544302, 544306, C07D23902, A01N 4354

Patent

active

051419432

ABSTRACT:
5-benzyl barbiturate compounds for use as water-soluble uridine phosphorylase inhibitors are disclosed. These compounds are useful for reducing the toxicity and anemia induced by antiviral drugs such as AZT, as well as for potentiating anticancer drugs and combatting their host-toxicity.

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