5-Benzothiazolesulfonamide derivatives for the topical treatment

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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548166, C07D27780, A61K 31425

Patent

active

044263880

ABSTRACT:
Novel carboxylic acid esters of 5-hydroxy-2-benzothiazolesulfonamide are shown to be useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are also disclosed, as well as methods for preparing the novel compounds.

REFERENCES:
patent: 2595334 (1952-05-01), Clapp et al.
patent: 2868800 (1959-01-01), Korman et al.
Akerfeldt, S., J. of Med. Chem., 1970, vol. 13, No. 5, 1012-1013.

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