5-aryl-substituted-2,3-dihydro-imidazo[1,2-a]furo- and thieno py

Details 5-aryl-substituted-2,3-dihydro-imidazo[1,2-a]furo- and thieno py 5-aryl-substituted-2,3-dihydro-imidazo[1,2-a]furo- and thieno py

1989-06-09

1991-02-12

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

5142285, 5142332, 514255, 514293, 514212, 544 60, 544126, 544361, 540599, 546 14, 546 84, A61K 3134, A61K 3138, A61K 31435, C07D49114

Patent

active

049924281

ABSTRACT:
The invention discloses certain 5-aryl-substituted,2,3-dihydro-imidazo[1,2-a]furo- and thieno pyridines useful as PAF receptor antagonists and for treating tumors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibiting PAF-mediated bronchoconstriction and extravasation, for controlling hyperreactive airways, for protecting against endotoxin-induced hypotension and death and for treating tumors.

REFERENCES:
patent: 4100165 (1978-07-01), Houlihan
patent: 4101553 (1981-07-01), Houlihan
patent: 4279912 (1981-07-01), Ager et al.

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