5-aryl-11-substituted-5H,11H-pyrrolo[2,1-][1,4]benzoxazepines as

Details 5-aryl-11-substituted-5H,11H-pyrrolo[2,1-][1,4]benzoxazepines as 5-aryl-11-substituted-5H,11H-pyrrolo[2,1-][1,4]benzoxazepines as

1988-10-11

1989-09-12

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C07D49804, A61K 3155

Patent

active

048657646

ABSTRACT:
There are disclosed compounds of the formula, ##STR1## where X and Y are each independently hydrogen, loweralkyl, halogen or trifluoromethyl; Z is hydrogen or 2- or 3-Cl, Br, I, CHO or CH.dbd.CR.sub.1 R.sub.2 where R.sub.1 and R.sub.2 are each independently hydrogen or loweralkyl; R is hydrogen, ##STR2## where n is 1, 2 or 3, R.sub.3 is loweralkyl, and R.sub.4 is hydrogen or loweralkyl, or alternatively the group --NR.sub.3 R.sub.4 as a whole is ##STR3## where R.sub.6 is loweralkyl, ##STR4## and R.sub.7 is loweralkyl or ##STR5## R.sub.8 being hydrogen, loweralkyl, halogen, trifluoromethyl or methoxy; and R.sub.5 is hydrogen, loweralkyl or arylloweralkyl.

REFERENCES:
patent: 4029672 (1977-06-01), Effland et al.
patent: 4045448 (1977-08-01), Effland et al.
patent: 4053599 (1977-10-01), Effland et al.
patent: 4608374 (1986-08-01), Effland et al.
patent: 4681879 (1987-07-01), Effland et al.

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