Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-05-28
1999-09-14
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514422, 5142355, 514340, 514255, 548539, 548517, 5462791, 544372, 544141, C07D40106, A61K 3144
Patent
active
059523689
ABSTRACT:
Compounds selected from the group of compounds represented by formula I: ##STR1## where: R.sub.10 is represented by the formula (A), (B), or (C): ##STR2## R.sub.20 is represented by the formula (U), (V), or (W): ##STR3## and the other substituents are as defined in the specification; and their pharmaceutically acceptable salts; are inhibitors of prostaglandin G/H synthase and are anti-inflammatory and analgesic agents.
REFERENCES:
patent: 3752826 (1973-08-01), Carson
patent: 5622948 (1997-04-01), Dunn et al.
CA 101:191609 Kaiser et al., 1984.
Kertesz Denis J.
Reuter Deborah C.
Sjogren Eric B.
Toscani Edvige Galeazzi
Fan Jane
Peries Rohan
Syntex (U.S.A.) Inc.
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