5-aroylnaphthalene derivatives as anti-inflammatory agents

Details 5-aroylnaphthalene derivatives as anti-inflammatory agents 5-aroylnaphthalene derivatives as anti-inflammatory agents

1999-06-21

2000-11-21

Aulakh, Charanjit S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 72, 549 61, 549 68, 549488, 549474, 549480, 546286, 546290, 546304, 546314, 546343, 514473, 514471, 514354, 514352, 514345, 514344, A61K 31381, C07D33322

Patent

active

061503975

ABSTRACT:
The present invention relates to certain 5-aroylnaphthalene derivatives of formula (I): ##STR1## that are inhibitors of prostaglandin G/H synthase, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

REFERENCES:
patent: 3655679 (1972-04-01), Shen et al.
patent: 3715358 (1973-02-01), Witzel et al.
patent: 3755455 (1973-08-01), Houlihan
patent: 3899529 (1975-08-01), Witzel
patent: 4226783 (1980-10-01), Marsh
patent: 4406896 (1983-09-01), Higuchi et al.
patent: 4980509 (1990-12-01), Maignan et al.
patent: 5484795 (1996-01-01), Bryant et al.
patent: 5484796 (1996-01-01), Bryant et al.
patent: 5484797 (1996-01-01), Bryant et al.
patent: 5491140 (1996-02-01), Bruns, Jr. et al.
Kassack, M. et al.: Rapid, highly sensitive gradient narrow bore high-performance liquid chromatographic detemination of suramin and its analogues. J. of Chromatogr. B, vol. 686, pp. 275-284, 1996.
Mazaleyrat, et al., Tetrahedron Letters, vol. 26:49, (1985), pp 6071-6074, "Participation of a Peri-Hydroxyl Group in the Trifluoroacetolysis of Napthalenesulfonamides".
Mustafa, J. Chemical Society, (1949,, pp 2151-2152, "Action of Grignard Solutions. Part III. Action of Gringard Solutions on Naphthasultone and its Substituted Derivatives."
Chemical Abstract; EN; (1960) p. 1473.
Chemical Abstract; Dziewonski, Moszew; Rocz. Chem., vol. 11., (1931), pp. 169-192.
Chemical Abstract; Chem. Zentralbl, vol. 102; (1931) pp 2876-2879.
Chemical Abstract; American Chemical Society, vol. 26, (1932) pp 130-131.

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