5-amino-6,8-difluoroquinolones as antibacterial agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...


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544363, 546156, A61K 3147, C07D40110




Novel 7-piperazino and 7-N-methylpiperazino derivatives of 5-amino-1-cyclopropyl-6,8-dihydro-1,4-dihydro-4-oxoquinoline-3-carboxylic acids as antibacterial agents are described as well as methods for their manaufacture, formulation, and use in treating bacterial infections.

patent: 3963736 (1976-06-01), Nakagome
Wise Antimicrobial Agents and Chemotherapy 4/83, pp. 559-564.


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