5-amino-5,6,7,8-tetrahydroquinolines and related compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546183, C07D21527

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active

052161641

ABSTRACT:
Novel 5-amino-5,6,7,8-tetrahydroquinolines and related compounds, intermediates and processes for the preparation thereof, and methods for relieving memory dysfunction utilizing compounds or compositions thereof are disclosed.

REFERENCES:
Weber et al., Chemical Abstracts, vol. 106 (1987) 196225b.
Y. C. Martin, et al., Journal of Medicinal Chemistry, vol. 16, 147-150 (Feb., 1973), entitled "Potential Anti-Parkinson Drugs Designed by Receptor Mapping".
L. Mosti, et al., Journal of Heterocyclic Chemistry, vol. 22, 1503-1509 (Nov.-Dec., 1985), entitled "Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles V; and Synthesis of 5-Acyl-1,2-dihydro-2-oxo-3-pyridinecarbonitriles and 1,2,5,6,7,8-Hexahydro-2,5-dioxo-3-quinoline-carboxamides and 1,2,5,6,7,8-Hexahydro-2,5-dioxo-3-quinolinecarboxamides".
R. Albrecht and E. Schroder, Archiv Der Pharmazie, vol. 308; 588-594 (1975), entitled "Chemotherapeutic Nitroheterocycles, 17.sup.1) Condensation Products of Nitrated Heterocyclic Aldehydes with Oxocyclopentathiophenes and Oxotetrahydroquinolines", and English translation.

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