Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1981-02-23
1982-06-15
Springer, David B.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
548436, A61K 3140, C07D20980
Patent
active
043351352
ABSTRACT:
Novel trans cyclohept[c,d]indolols of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and optionally substituted aralkyl of 7 to 12 carbon atoms and R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms and optionally substituted aralkyl of 7 to 12 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having hypotensive and antihypertensive activity and a process for their preparation.
REFERENCES:
patent: 3106559 (1963-10-01), Sunagawa et al.
patent: 3397202 (1968-08-01), Plostnieks
Uhle J. ACS, 71, pp. 761-766 (1949).
Brown Neil L.
Dumont Claude
Frechet Daniel
Nedelec Lucien
Plassard Guy
Roussel Uclaf
Springer David B.
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