5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3

Details 5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3 5-Alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl-1,2-dihydro-3

1979-08-31

1980-11-04

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

26032625, 26032646, 2603265S, 2603265SF, 26037662, C07D48704, A61K 3140

Patent

active

042320380

ABSTRACT:
Novel 5-alkylsulfinylbenzoyl- and 5-alkylsulfonylbenzoyl,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid compounds represented by the formula ##STR1## and the pharmaceutically acceptable, non-toxic esters and salts thereof, wherein n is 1 or 2, R is hydrogen or a lower alkyl group containing from 1-4 carbon atoms and R.sup.1 is a lower alkyl group having from 1-4 carbon atoms at the ortho, meta or para postions of the benzoyl group and process for the production of such compounds. These compounds are useful as anti-inflammatory, analgesic and antipyretic agents and as smooth muscle relaxants.

REFERENCES:
patent: 4087539 (1978-05-01), Muchowski et al.
patent: 4089969 (1978-05-01), Muchowski et al.
patent: 4097579 (1978-06-01), Muchowski et al.
patent: 4140698 (1979-02-01), Van Horn et al.
Kochetkov et al.; Chem. Abs. vol. 55:1574g (1961).
Brandange et al.; Chem. Abs. vol. 76:25024t (1972).
Carelli et al.; Chem. Abs. vol. 59:7463g (1963).

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