5-(alkylidene-cycloalkyl)-and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S252050, C514S255050, C514S269000, C514S272000, C514S341000, C514S407000, C544S182000, C544S238000, C544S297000, C544S316000, C544S405000, C546S275400, C546S276100, C548S368100, C548S368400, C548S369100, C548S370100, C548S371100, C548S371700, C548S372100, C548S372500

Reexamination Certificate

active

06838458

ABSTRACT:
The present invention relates to 5-(alkylidene-cycloalkyl)-pyrazoles and 5-(alkylidene-heterocyclyl)-pyrazoles of the formula I:wherein the ring of the formula (R5)-A-(SOmR4), m, B, ring G, R1through R7are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.

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