5-alkoxy tryptamine derivatives

Details 5-alkoxy tryptamine derivatives 5-alkoxy tryptamine derivatives

1996-05-30

1997-08-05

McKane, Joseph K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548208, 548210, 548451, 548455, 548468, 548503, C07D20908, C07D22106

Patent

active

056544316

ABSTRACT:
Novel 5-alkoxy tryptamine derivatives are provided, corresponding to the general formula: ##STR1## in which R may be alkaline, X may be amino, and Y is various N-heterocyclic or N-branched chain moieties. The compounds show selective binding to 5-HT.sub.1D receptor subtypes, and have potential pharmaceutical utility in manufacture of migraine-treating drugs.

REFERENCES:
CA114:178477w 5-HT.sub.1D serotonin . . . investigation. Glennon et al., p. 84, 1991.
CA122:2652446 b Preparation . . . ligands. Halazy et al., p. 1091, 1995.
CA 121:179613u Preparation of . . . ligands, Halazy et al. p. 1085, 1994.

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