Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-08-25
1995-06-27
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514346, 514349, A61K 3144, C07D21355, C07D21356, C07D21357
Patent
active
054280451
ABSTRACT:
Novel 5-acyl-2-(1H)pyridinones and their use as cardiotonic agents. Typical of the compounds is 5-acetyl-1,2-dihydro-6-methyl-2-oxo-3-pyridinecarbonitrile which is prepared by condensing anionic cyano acetamide with 3-[(dimethylamino)methylenyl]-2,4-pentanedione in an inert organic solvent.
REFERENCES:
patent: 4568751 (1986-02-01), Jones et al.
patent: 4731371 (1988-03-01), Jones et al.
patent: 4992452 (1991-02-01), Jones et al.
Dage Richard C.
Jones Winton D.
Schnettler Richard A.
Merrell Dow Pharmaceuticals Inc.
Rotman Alan L.
Sayles Michael J.
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