5,9.alpha.-Imino- or 6,9.alpha.-iminomethylene-9-deoxy-PGF.sub.1

Details 5,9.alpha.-Imino- or 6,9.alpha.-iminomethylene-9-deoxy-PGF.sub.1 5,9.alpha.-Imino- or 6,9.alpha.-iminomethylene-9-deoxy-PGF.sub.1

1978-04-05

1979-01-23

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546183, 542429, C07C17700

Patent

active

041360958

ABSTRACT:
This invention relates to certain structural and pharmacological analogs of prostacyclin (PGI.sub.2) wherein a nitrogen is substituted for the 6,9.alpha.-epoxy-oxygen of prostacyclin. These novel nitrogen-containing prostacyclin-type compounds are useful for the pharmacological purposes for which prostacyclin is used, e.g., as antithrombotic agents, antihypertensive agents, antiasthma agents, nasal decongestants, or regulators of tertility and procreation.

REFERENCES:
patent: 3772312 (1973-11-01), Sturm et al.

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