5'-(8'-Hydroxyquinolyl)guanidine compounds

Details 5'-(8'-Hydroxyquinolyl)guanidine compounds 5'-(8'-Hydroxyquinolyl)guanidine compounds

1974-10-29

1976-03-30

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424258, C07D21538

Patent

active

039474550

ABSTRACT:
A novel aromatic guanidine compound having the formula: ##SPC1##
Is found to have biological activity. This guanidine compound and its salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.

REFERENCES:
Ciba Ltd., Chem. Abstr., Vol. 57, Col. 3420d, 1960.
Gulland et al., Chem. Abstr., Vol. 44, Col. 3497, 1950.
Chandran et al., J. Sci. Ind. Res., Vol. 11, pp. 129-132, 1952.
Royer, J. Chem. Soc., (London), pp. 1665-1666, 6/1949.

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