5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones

Details 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones 5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones

2006-08-29

2006-08-29

McKenzie, Thomas C. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S264110

Reexamination Certificate

active

07098332

ABSTRACT:
The invention provides 5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one compounds that are selective inhibitors of KDR and FGFR kinases, and are useful in the treatment of cancers. The compounds have the generic structure Iwhere Ar, Ar′, and R1are as set forth in the present specification. The invention also provides pharmaceutical compositions containing these compounds and methods for their use.

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patent: WO 02/18380 (2002-03-01), None

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