Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-14
2011-06-14
Moore, Susanna (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S255000
Reexamination Certificate
active
07960395
ABSTRACT:
There are disclosed novel 5,7-disubstituted [1,3]thiazolo[4,5-d]pyrimidin-2(3H)-one derivatives of formula (I)wherein R1, R2, R3, R4and n are as defined in the specification, and pharmaceutically acceptable salts thereof, together with processes for their preparation, pharmaceutical compositions comprising them and their use in therapy. The compounds of formula (I) are CX3CR1 receptor antagonists and are thereby particularly useful in the treatment or prophylaxis of neurodegenerative disorders, demyelinating disease, cardio- and cerebrovascular atherosclerotic disorders, peripheral artery disease, rheumatoid arthritis, pulmonary diseases such as COPD, asthma or pain.
REFERENCES:
patent: 00/09511 (2000-02-01), None
patent: 01/25242 (2001-04-01), None
patent: 01/58906 (2001-08-01), None
patent: 01/58907 (2001-08-01), None
patent: 02/076990 (2002-10-01), None
patent: 2004/026835 (2004-04-01), None
patent: 2004/026880 (2004-04-01), None
patent: 2005/033115 (2005-04-01), None
patent: 2006/064228 (2006-06-01), None
patent: 2006/107257 (2006-10-01), None
patent: 2006/107258 (2006-10-01), None
Vippagunta et. al. (Advanced Drug Delivery Reviews, 2001, 48, pp. 3-26).
Johansson Rolf
Karlström Sofia
Kers Annika
Nordvall Gunnar
Rein Tobias
Astrazeneca AB
Connolly Bove & Lodge & Hutz LLP
Moore Susanna
LandOfFree
5,7-disubstituted thiazolo[4,5-d]pyrimidines for the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 5,7-disubstituted thiazolo[4,5-d]pyrimidines for the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5,7-disubstituted thiazolo[4,5-d]pyrimidines for the... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2726659