5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-(1-propyl))pip eridinyl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546196, A61K 31445, C07D40504

Patent

active

052927512

ABSTRACT:
The present invention relates to 5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl))piperidinyl]-4H-1-benz opyran-4-one its preparation and its use.
5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl))piperidinyl]-4H-1-benzo pyran-4-one is useful for the treatment of arthritis and/or rheumatism and for the treatment of chronic inflammatory diseases.

REFERENCES:
patent: 4900727 (1990-02-01), Kattige
The Structure Of Rohitukene, The Main Alkaloid Of Amoora Rohituka (Syn. Aphanamixis Polystachya) (Meliaceae), A. D. Harmon et al., Tetrahedron Letters, No. 8, (1979) pp. 721-724.
An Antiinflammatory Cum Immunomodulatory Piperidinylbenzopyranone From Dysoxylum Binectariferum : Isolation, Structure and Total Synthesis, R. A. Naik et al., Tetrahedron vol. 44, No. 7, (1988) pp. 2081-2086.

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