5-6 to 5-7 Heterobicycles as factor Xa inhibitors

Details 5-6 to 5-7 Heterobicycles as factor Xa inhibitors 5-6 to 5-7 Heterobicycles as factor Xa inhibitors

2005-11-01

2005-11-01

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S303000, C544S330000, C544S331000, C544S332000, C546S119000

Reexamination Certificate

active

06960595

ABSTRACT:
The present application describes 5-6 or 5-7 heterobicyclics of Formula I:or pharmaceutically acceptable salt forms thereof, wherein ring P is a 5-membered heteroaromatic and ring M is a 6 or 7-membered non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

REFERENCES:
patent: 6506771 (2003-01-01), Pinto et al.
patent: WO 95/01980 (1995-01-01), None
patent: WO 00/39131 (2000-07-01), None
patent: WO 02/00655 (2002-01-01), None

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