5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the t

Details 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the t 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the t

1985-06-28

1986-09-09

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549459, A61K 31335, C07D30700, A61K 31557

Patent

active

046110062

ABSTRACT:
5,6-Epoxy-7-oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein X is O or ##STR2## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for example, in the treatment of thrombotic disease.

REFERENCES:
patent: 4073933 (1978-02-01), Shimomura
patent: 4143054 (1979-03-01), Sprague
patent: 4187236 (1980-02-01), Sprague
patent: 4220594 (1980-09-01), Sprague
patent: 4228180 (1980-10-01), Sprague
patent: 4254044 (1981-03-01), Sprague

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