Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-09-23
2010-10-19
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S119000
Reexamination Certificate
active
07816351
ABSTRACT:
Disclosed herein are 5,β-dimethylthieno[2,3-d]pyrimidine derivatives useful as antiviral agents. More particularly, disclosed are 5,β-dimethylthieno[2,3-djpyrimidine derivatives represented by Formula 1, having an excellent inhibitory effect on the proliferation of hepatitis C virus (HCV), pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition for the prevention and treatment of hepatitis C virus (HCV), containing, as active ingredients, these compounds. The 5,6-dimethylthieno[2,3-d]pyrimidine derivatives represented by Formula 1 have an excellent effect of inhibiting the proliferation of hepatitis C virus and also have low toxicity. Thus, these compounds are available as agents for the prevention and treatment of hepatitis C.
REFERENCES:
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patent: 82023 (1983-06-01), None
patent: 2005047292 (2005-05-01), None
Davis, et al. “Treatment of Chronic Hepatitis C with Recombinant Interferon Alfa; A Multicenter Randomized, Controlled Trial” New England Journal of Medicine, 321, 1501, 1989.
Harvey J. Alter “Chronic Consequences of Non-A, Non-B Hepatitis” Current Persepective in Hepatology, p. 83, 1989.
Han Cheol Kyu
Kim Jin-ah
Kim Nam-Doo
Yoon Jeonghyeok
Anderson Rebecca L
Equispharm Co., Ltd
Lucas & Mercanti LLP
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