5,6-Dihydroxy aminotetralol compounds

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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26050118, 26050119, 2605708R, 424316, C07C 8728, A01N 920

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active

041044029

ABSTRACT:
Novel aminotetralol compounds of the formula ##STR1## wherein Z.sup.1 and Z.sup.2 are hydrogen or an alkyl group and R.sup.1 is a substituted acyclic hydrocarbon group or a cyclic hydrocarbon group, and their pharmaceutically acceptable salts, have excellent pharmacological activities such as strong bronchodilating activity or .beta.-adrenergic blocking activity. They are useful as medicines, for example, for treatment of asthma or arrhythmia.

REFERENCES:
patent: 3135797 (1964-06-01), Biel
patent: 3930022 (1975-12-01), Hanck et al.
Thrift, "Jour. Chem. Soc. London", Series C, pp. 288-293 (1967).

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