5,6-Dihydroxy aminotetralol compounds

Details 5,6-Dihydroxy aminotetralol compounds 5,6-Dihydroxy aminotetralol compounds

1975-03-04

1977-03-01

Wyman, Daniel E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602564R, 260288R, 26029387, 260296R, 2603068R, 260307R, 26032615, 260329AM, 260333, 2605011, 26050118, 26050119, 26050121, 260559A, 260566R, 2605708R, 260571, 260574, 424330, C07C 9106, C07C 9142, C07C 9314, A61K 31135

Patent

active

040102025

ABSTRACT:
Novel aminotetralol compounds of the formula ##STR1## wherein Z.sup.1 and Z.sup.2 are hydrogen or an alkyl group and R.sup.1 is a substituted acyclic hydrocarbon group or a cyclic hydrocarbon group, and their pharmaceutically acceptable salts, have excellent pharmacological activities such as strong bronchodilating activity or .beta.-adrenergic blocking activity. They are useful as medicines, for example, for treatment of asthma or arrhythmia.

REFERENCES:
patent: 3534055 (1970-10-01), Gittos et al.
patent: 3579582 (1971-05-01), Symon
patent: 3751420 (1973-08-01), Hauck et al.
patent: 3930022 (1975-12-01), Hauck et al.
Thrift, "J. Chem. Soc., C", pp. 288-293 (1967).
Chiemprasert et al., "Ann. Chem.", Band 685, pp. 141-148 (1965).

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