Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1986-08-13
1987-06-23
Shippen, Michael L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514551, 514684, 560173, 560194, 568326, C07C10118, C07C 6960, C07C 6940, A61K 3122
Patent
active
046753419
ABSTRACT:
The invention relates to novel [(5,6-dichloro-3-oxo-9a-propyl-2,3,9,9a-tetrahydrofluoren-7-yl)oxy]ethanol , its derivatives, and their salts. The compounds are useful for the treatment and prevention of injury to the brain and of edema due to head trauma, stroke (particularly ischemic), arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, cerebral hemorrhage, cerebral tumors, encephalomyelitis, spinal cord injury, hydrocephalus, post-operative brain injury trauma, edema due to cerebral infections including that due to AIDS virus, various brain concussions and elevated intracranial pressure.
REFERENCES:
patent: 4316043 (1982-02-01), Cragoe
patent: 4317922 (1982-03-01), Cragoe
patent: 4337354 (1982-06-01), Cragoe
patent: 4356313 (1982-10-01), Cragoe
patent: 4356314 (1982-10-01), Cragoe
Caruso Charles M.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Shippen Michael L.
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