Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1973-12-26
1978-02-28
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31135
Patent
active
040768430
ABSTRACT:
5,6,7,8-Tetrahydronaphthalenes having the structure ##STR1## and the pharmaceutically acceptable salts thereof, are useful as blood pressure lowering agents. In the above formula R.sub.1 can be hydrogen or alkyl; R.sub.2 is alkyl; R.sub.3 and R.sub.4 can each be hydrogen, hydroxyl, alkoxy, or arylalkoxy, but both cannot be hydroxyl. Those compounds wherein at least one of R.sub.3 and R.sub.4 is other than hydrogen are novel, and constitute a part of this invention.
REFERENCES:
patent: 3579582 (1971-05-01), Symon
Chemical Abstracts, 63:8274-6 (1965).
Cimarusti Christopher M.
Hauck Frederic Peter
Sundeen Joseph E.
Barrack Donald J.
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Schenkman Leonard
Smith Merle J.
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