Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-03-13
1993-10-05
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514286, 546 16, 546 63, 546 70, A61K 31435, C07D47118, C07D47120
Patent
active
052505375
ABSTRACT:
5,6,7,8,9,10-Hexahydro-7,10-iminocyclohept[b]indole, 6,7,8,9,10,11-hexahydro-7,11-imino-5H-cyclooct[b]indole and substituted derivatives are effective in the treatment of psychoses with limited liability to produce concomitant adverse extrapyramidal symptoms. These compounds are also useful for treating other central nervous system and cardiovascular disorders.
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Abou-Gharbia et al. Med. Chem. 30, 1818-1823 (1987).
Axelsson et al. Psychopharmacology 104, 287-292 (1991).
Welch et al. J. Med. Chem. 23, 949-952 (1980).
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Harbert et al. Mol. Pharm. 17, 38-42 (1980).
Abreu Mary E.
Kaiser Carl
Mewshaw Richard E.
Appleby Vanessa L.
Datlow P.
Fabiano Vincent
Scios Nova Inc.
Shah Mukund J.
LandOfFree
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