5-(4-Fluorophenyl)tetrahydro-2-furanol

Details 5-(4-Fluorophenyl)tetrahydro-2-furanol 5-(4-Fluorophenyl)tetrahydro-2-furanol

1980-01-16

1981-07-07

Raymond, Richard

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30702

Patent

active

042774047

ABSTRACT:
2-Substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles of the formula (I): ##STR1## and the pharmaceutically-acceptable salts thereof, wherein the hydrogen atoms in the 4a position and 9b positions are in a trans relationship to each other and the 5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole moiety is dextrorotatory; X.sub.1 and Y.sub.1 are the same or different and are each hydrogen or fluoro; Z.sub.1 is hydrogen, fluoro or methoxy; M is a member selected from the group consisting of ##STR2## a mixture thereof and C.dbd.O and n is 3 or 4; their use as tranquilizing agents, pharmaceutical compositions containing them and a process for their production.

REFERENCES:
patent: 3932519 (1976-01-01), Cohen et al.
Fitzpatrick et al., Chemical Abstracts, vol. 71 (1969) 70550u.

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