5-(4-Amino or acylaminophenyl)-2(1H)-pyrazinones having inotropi

Details 5-(4-Amino or acylaminophenyl)-2(1H)-pyrazinones having inotropi 5-(4-Amino or acylaminophenyl)-2(1H)-pyrazinones having inotropi

1983-06-02

1985-12-03

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544120, 544405, 544408, C07D24118, C07D40312, C07D41312, C07D40112

Patent

active

045567115

ABSTRACT:
This invention relates to 5-(phenyl)-2(1H)-pyrazinones substituted in the 4-position of the phenyl ring by an amino or acylamino group. These compounds have inotropic activity. One specific compound is 5-(4-acetamidophenyl)-2(1H)-pyrazinone.

REFERENCES:
patent: 3745161 (1973-07-01), Tsung-Ying et al.
Greene ed., Protective Groups in Organic Synthesis, John Wiley & Sons, N.Y. (1981), pp. 222-249.
McOmie ed., Protective Groups in Organic Chemistry, Plenum Press, N.Y. (1973) pp. 46-61.
Sheradsky et al., J.C.S. Perkin I:1296-1299 (1977).
Ohta et al., Hukusokan Kagaku Toronkai Kuen Yoshishu 8th:84-88 (1975) (Chem. Abstr. 84:164,723Y).

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