5-(4-amino-3,5-dimethoxyphenyl)-5-hydroxy-barbituric acid

Details 5-(4-amino-3,5-dimethoxyphenyl)-5-hydroxy-barbituric acid 5-(4-amino-3,5-dimethoxyphenyl)-5-hydroxy-barbituric acid

1986-10-10

1988-10-04

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544305, C07D23962

Patent

active

047757566

ABSTRACT:
The invention relates to substituted phenylbarbituric acids of the formula ##STR1## wherein R.sup.1 and R.sup.3, independently, are lower-alkoxy or lower-alkylthio; R.sup.2 is lower-alkoxy, hydroxy or amino; and R.sup.4 is hydrogen; or R.sup.1 and R.sup.2 are lower-alkoxy, R.sup.3 is hydrogen and R.sup.4 is lower-alkyl,
which are prepared from correspondingly substituted benzene derivatives and alloxan. The compounds of formula I can be converted into substituted benzaldehydes which in turn are known intermediates in the preparation of pharmaceutically valuable benzylpyrimidines.

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King and Clark-Lewis, J. Chem. Soc. 3077 (1951).

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