Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-02-20
2007-02-20
Stockton, Laura L. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S317100
Reexamination Certificate
active
11205954
ABSTRACT:
5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,4-dione and analogues useful as inhibitors of macrophage elastase are disclosed.
REFERENCES:
patent: 6352976 (2002-03-01), Warshawsky et al.
patent: 2004/0067996 (2004-04-01), Sheppeck
patent: 2004/0072871 (2004-04-01), Dublanchet et al.
patent: 1288199 (2003-05-01), None
patent: WO 00/40577 (2000-07-01), None
patent: WO 02/074752 (2002-09-01), None
patent: WO 02/096426 (2002-12-01), None
patent: WO 2004/020412 (2004-03-01), None
Golub et al., Science, vol. 286, Oct. 15, 1999, pp. 531-537.
R. Dean Hautamaki et al., Requirementfor Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice,Science, vol. 277 p. 2002-2004 (Sep. 26, 1997).
Rosco L. Warner et al., Role of Metalloelastase (MMP-12) in a Mdel of Experimental Asthma,Experimental Biology(2002): Meeting Abstracts, A590, 456.8.
Steven D. Shapiro et al., Cloning and Characterization of a Unique Elastolytic Metalloproteinase by Human Alveolar Macrophages,Journal of Biological Chemistry, vol. 268, No. 32, Issue of Nov. 15, 1993,pp. 23824-23829.
Shun-ichiro Matsumoto et al., Expression and Localization of Matrix Metalloproteinase-12 in the Aorta of Cholesterol-Fed Rabbits,American Journal of Pathology, vol. 153, No. 1, Jul. 1998, p. 109-119.
Yoshikatsu Kaneko, et al., Macrophage Metalloelastase as a Major Factor for Glomerular Injury in Anti-Glomerular Basement Membrane Nephritis,Journal of Immunology, p. 3377-3385 (2003).
Sofia Jormsjo et al., Allele-Specific Regulation of Matrix Metalloproteinase-12 Gene Activity Is Associated with Coronary Artery Luminal Dimensions in Diabetic Patients with Manifest Coronary Artery Disease,Circulation Research, (2000; 86:998-1003).
Cohen Pontani Lieberman & Pavane LLP
Quest Pharmaceutical Services
Stockton Laura L.
LandOfFree
5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3808764