5-[2(Or 3)-hydroxyphenylsulfonyl]thiophene-2-sulfonamides for th

Details 5-[2(Or 3)-hydroxyphenylsulfonyl]thiophene-2-sulfonamides for th 5-[2(Or 3)-hydroxyphenylsulfonyl]thiophene-2-sulfonamides for th

1985-08-12

1986-04-29

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514913, A61K 3138

Patent

active

045857873

ABSTRACT:
5-[2(or 3)-Hydroxyphenylsulfonyl]thiophene-2-sulfonamides are useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are disclosed.

REFERENCES:
patent: 4029809 (1975-07-01), Smith et al.
patent: 4386098 (1983-05-01), Woltersdorf et al.
patent: 4416890 (1982-05-01), Woltersdorf
patent: 4426388 (1982-04-01), Woltersdorf
patent: 4454148 (1982-12-01), Woltersdorf
patent: 4456599 (1983-04-01), Woltersdorf
patent: 4477466 (1983-05-01), Shepard
patent: 4499103 (1983-03-01), DeSolms
patent: 4542152 (1983-05-01), Shepard
Gelatt et al., Am. J. Vet. Res., 40, 334-345 (1979).
Havener, Ocular Pharmacology, pp. 395-416 (1966).

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