5-(2-Carboxythiophen-5-y l)-16-aryloxy-.alpha.-tetranor-.omega.-

Details 5-(2-Carboxythiophen-5-y l)-16-aryloxy-.alpha.-tetranor-.omega.- 5-(2-Carboxythiophen-5-y l)-16-aryloxy-.alpha.-tetranor-.omega.-

1975-09-29

1977-12-27

Helfin, Bernard

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603323R, 2603325, 424275, C07D33324, A01N 900

Patent

active

040654729

ABSTRACT:
5-(2-Carboxythiophen-5-yl)-16-aryloxy-.alpha.-tetranor-.omega.-tetranorpros taglandins and intermediates useful in their preparation are disclosed. The novel prostaglandins of this invention have been found to have activity profiles comparable to the parent prostaglandins but they exhibit a greater tissue specificity of action.

REFERENCES:
patent: 3922289 (1975-11-01), Patterson et al.

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