Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-23
1994-12-27
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
424 10, A61K 31505, A61K 4900
Patent
active
053766580
ABSTRACT:
The present invention relates to the compound 5,10-methylene-tetrahydrofolate (CH.sub.2 FH.sub.4), and its solution product isomer FH.sub.4, therapeutic uses of these compounds, and compositions thereof. CH.sub.2 FH.sub.4 and FH.sub.4 strongly modulate the in vivo antitumor effects of 5-Fluorouracil.
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Wood, et al., Chemical Abstracts 109:9
Gustavsson Bengt G.
Spears Colin P.
Cintins Marianne M.
Criares T. J.
University of Southern California
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