Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-12-26
1977-05-10
Jiles, Henry R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
42424854, 424250, 424258, 2602475GP, 260268BQ, 260287R, 260288R, 260288CE, 260289K, C07D21526, C07D41306
Patent
active
040227766
ABSTRACT:
5-[Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-carbostyril derivatives represented by the formula (I) ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different, each represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an aralkyl group containing a straight or branched chain alkyl moiety having 1 to 4 carbon atoms or a cycloalkyl group having 4 to 6 carbon atoms, or R.sup.1 and R.sup.2 may, when taken together with the nitrogen atom to which they are attached, form a 5 or 6-membered substituted or unsubstituted heterocyclic ring containing 1 or 2 nitrogen, oxygen or sulfur atoms as hetero atoms, the pharmaceutically acceptable acid addition salts thereof and a process for preparing the above compounds.
REFERENCES:
patent: 2770619 (1956-11-01), Schraufstatter et al.
patent: 3444173 (1969-05-01), Goldman
patent: 3644353 (1972-02-01), Lunts et al.
Snyder, Organic Synthetics, vol. 28, p. 26-27, (1948).
Nakagawa Kazuyuki
Tamada Shigeharu
Tanimura Kaoru
Yoshizaki Shiro
Jiles Henry R.
Otsuka Pharmaceutical Company Limited
Ramsuer R. W.
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