5-(1-Hydroxy-2-(heterocyclic amino))ethyl-8-hydroxy-3,4-dihydroc

Details 5-(1-Hydroxy-2-(heterocyclic amino))ethyl-8-hydroxy-3,4-dihydroc 5-(1-Hydroxy-2-(heterocyclic amino))ethyl-8-hydroxy-3,4-dihydroc

1976-06-30

1978-01-10

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

260268BQ, 260287K, 260288CE, 260289K, 42424854, 424250, 424258, C07D41306, C07D40106

Patent

active

040680762

ABSTRACT:
5-[1-HYDROXY-2-(HETEROCYCLIC AMINO)]ETHYL-8-HYDROXY-3,4-DIHYDROCARBOSTYRIL DERIVATIVES REPRESENTED BY THE FORMULA (I) wherein A, when taken together with the nitrogen atom to which it is attached, forms a 6-membered substituted or unsubstituted heterocyclic ring containing 1 or 2 nitrogen, or oxygen atoms as hetero atoms, the pharmaceutically acceptable acid addition salts thereof, and a process for preparing the above compounds.

REFERENCES:
patent: 3444173 (1969-05-01), Goldman
patent: 3975391 (1976-08-01), Nakagawa et al.
patent: 3994901 (1976-11-01), Nakagawa et al.
Morrison et al.; Organic Chemistry (1969) pp. 666, 866, 567.
Chodorekar et al., J. Med. Chem., vol. 15 (1972) pp. 49-57.
J. Med. Chem. vol. 15, pp. 260-266 (1972).
Imp. Chem. Ind. Ltd.; Chem. Abs. vol. 621, 16212e (1965).

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